Boron

Many anecdotal alternative treatments with clandestine sources of trace elements abound in the literature. For example, matrix metalloproteinase (MMP)-2 and MMP-9 are involved in keratinocyte migration and granulation tissue remodeling during wound healing. Thermal water cures are sometimes proposed as complementary treatment for accelerating healing of wounds resulting from burns or surgery, but their mechanisms of action remain unknown. Some thermal waters are rich in trace elements, such as boron and manganese. Clinical studies have also shown beneficial effects of trace elements, such as boron and manganese, for human wound healing.67

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