Special Medications

-Ranitidine (Zantac) 50 mg IV bolus, then continuous infusion at 12.5 mg/h

[300 mg in 250 mL D5W over 24h (11 cc/h)], or 50 mg IV q6-8h OR -Cimetidine (Tagamet) 300 mg IV bolus, then continuous infusion at 50 mg/h

(1200 mg in 250 cc D5W over 24h), or 300 mg IV q6-8h OR -Famotidine (Pepcid) 20 mg IV q12h.

-Vitamin K (Phytonadione) 10 mg IV/SQ qd for 3 days (if INR is elevated). Esophageal Variceal Bleeds:

-Somatostatin (Octreotide) 50 mcg IV bolus, followed by 25-50 mcg/h IV infusion (1200 mcg in 250 mL of D5W at 11 mL/h).

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