Or

-Fluconazole (Diflucan) 400-800 mg PO qd for 8-12 weeks Suppressive Treatment of Cryptococcus:

-Fluconazole (Diflucan) 200 mg PO qd indefinitely.

Active Tuberculosis:

-Isoniazid (INH) 300 mg PO qd; and rifampin 600 mg PO qd; and pyrazinamide 15-25 mg/kg PO qd (500 mg bid-tid); and ethambutol 15-25 mg/kg PO qd (400 mg bid-tid). -All four drugs are continued for 2 months; isoniazid and rifampin are continued for a period of at least 9 months and at least 6 months after the last negative cultures. -Pyridoxine (Vitamin B6) 50 mg PO qd concurrent with INH. Prophylaxis for Inactive Tuberculosis:

-Isoniazid 300 mg PO qd; and pyridoxine 50 mg PO qd for 12 months.

Disseminated Mycobacterium Avium Complex (MAC): -Clarithromycin (Biaxin) 500 mg PO bid AND Ethambutol 800-1000 mg qd; with or without rifabutin 450 mg qd. Prophylaxis against MAC: -Azithromycin (Zithromax) 1200 mg once a week.

Disseminated Coccidioidomycosis:

-Amphotericin B 0.5-0.8 mg/kg IV qd, to a total dose 2.0 gm OR -Fluconazole (Diflucan) 400-800 mg PO or IV qd.

Disseminated Histoplasmosis:

-Amphotericin B 0.5-0.8 mg/kg IV qd, to a total dose 15 mg/kg OR -Fluconazole (Diflucan) 400 mg PO qd. OR

-Itraconazole (Sporanox) 300 mg PO bid for 3 days, then 200 mg PO bid.

Suppressive Treatment for Histoplasmosis: -Fluconazole (Diflucan) 400 mg PO qd OR -Itraconazole (Sporanox) 200 mg PO bid.

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