A-a gradient = [(PB-PH2O) FiO2 - PCO2/R] - PO2 arterial
PB = 760 mmHg; PH2O = 47 mmHg ; R = 0.8 normal Aa gradient <10-15 mmHg (room air)
Arterial oxygen capacity =(Hgb(gm)/100 mL) x 1.36 mL O2/gm Hgb
Arterial O2 content = 1.36(Hgb)(SaO2)+0.003(PaO2)= NL 20 vol%
O2 delivery = CO x arterial O2 content = NL 640-1000 mL O2/min
Cardiac output = HR x stroke volume
Na (mEq) deficit = 0.6 x (wt kg) x (desired [Na] - actual [Na]) SVR = MAP-CVP x 80 = NL 800-1200 dyne/sec/cm2
72 (males) x serum creatinine (mg/dL) 85 (females) x serum creatinine (mg/dL)
Creatinine clearance = U creatinine (mg/100 mL) x U vol (mL) _
P creatinine (mg/100 mL) x time (1440 min for 24h)
Normal creatinine clearance = 100-125 mL/min(males), 85-105(females)
Body water deficit (L) = 0.6(weight kg)([measured serum Na]-140) 140
Serum Osmolality = 2 [Na] + BUN + Glucose = 270-290 2.8 18
Na (mEq) deficit = 0.6 x (wt kg)x(desired [Na] - actual [Na])
Fractional excreted Na = U Na/ Serum Na x 100 = NL<1% U creatinine/ Serum creatinine
For each 100 mg/dL increase in glucose, Na decreases by 1.6 mEq/L.
Corrected = measured Ca mg/dL + 0.8 x (4 - albumin g/dL)
Predicted Maximal Heart Rate = 220 - age
60 70 80 90 100
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