Management of Secondary Complications of ARF

1. Infections. Often related to catheters and results in sepsis. Treat aggressively with antibiotics but do not use prophylactic antibiotics. Remove catheters as early as possible.

2. GI bleeding. Related to stress and platelet dysfunction in uremia.

a. Proton-pump inhibitors. No dose adjustment is necessary; give omeprazole, 1 mg/kg.

b. H2 antagonist. Need to reduce dose by 50%.

3. Anemia. Usually well tolerated and often related to blood drawing. Epogen is of limited use.

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