Pharmacologic Management

1. Antibiotic therapy. Necessary to prevent sight-threatening complications of gonococcal, chlamydial, and herpes conjunctivitis in neonates.

a. Gonococcal. Aqueous penicillin G or ceftriaxone for 1-7 days and ocular irrigation.

b. Chlamydial. Oral erythromycin for 14 days.

c. Herpes simplex. Topical trifluorothymidine 9 times a day for at least 14 days with or without systemic acyclovir.

2. Topical antibiotic treatment. Erythromycin, tetracycline, or polymyxin B solution qid for bacterial conjunctivitis hastens resolution of symptoms but may not be necessary when oral medications are administered.

3. Antiviral therapy. Except for HSV, no specific treatment is available.

4. Topical antihistamine or mast cell stabilizer. For allergic conjunctivitis.

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