Acquired disorders

a. Aplastic anemia.

b. Infection.

c. Marrow infiltrative processes (leukemia, rhabdomyosarco-ma, neuroblastoma, Ewing sarcoma, Langerhans cell histi-ocytosis, storage diseases).

d. Secondary to drugs or radiation.

e. Osteopetrosis.

f. Paroxysmal nocturnal hemoglobinuria.

g. Neonatal hypoxia or placental insufficiency.

h. Nutritional deficiencies (iron, folate, vitamin B 12), anorexia nervosa.

i. Myelodysplastic syndrome.

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