Stargardts Disease Definition

This is a macular dystrophy that proceeds from the retinal pigment epithelium.

Inheritance: Autosomal recessive disorder. Epidemiology: Stargardt's disease is rare.

Symptoms: Progressive loss of visual acuity occurs between the ages of 10 and 20 years.

Findings and diagnostic considerations: Initial findings are slight with white "fleck" lesions in the macular region (Fig. 12.29), which may occur in combination with lesions in the entire fundus (fundus flavimaculatus). The electroretinogram and electro-oculogram will be normal or reduced. In the later stage, the white lesions significantly increase in size and number. This will not necessarily be reflected in the ERG or EOG.

Differential diagnosis: Other disorders involving white "fleck" lesions such as inherited autosomal dominant drusen must by excluded by ophthalmoscopy. The diagnosis is confirmed by fluorescein angiography. Blockage of the choroidal fluorescein is a characteristic feature of Stargardt's disease.

Treatment: No treatment is available. Edge-filtered eyeglasses and magnifying near vision aids can help make better use of the patient's remaining vision.

— Stargardt's disease.

— Stargardt's disease.

of the pigment epithelium in the macular region.

Typical "fleck" lesions of the retina (arrow) and extensive atrophy

Fig. 12.29

of the pigment epithelium in the macular region.

Typical "fleck" lesions of the retina (arrow) and extensive atrophy

Fig. 12.29

Prophylaxis: No prophylaxis is possible. Examination of siblings and genetic counseling are indicated.

Clinical course and prognosis: The disorder is chronically progressive. Vision in the final stages is usually 0.1 (20/200) or less.

Discarding Negative Habits

Discarding Negative Habits

I ought to change, but I've attempted and failed. Does this seem familiar? Frequently, altering habits does seem insurmountable. A lot of us merely don't have enough motivation to alter our habits all of our foul habits in a way that would really affect our life. We hold them tight as we view them as rewards. But your habits determine your life. Discarding Negative Habits Methods That Will Help You Deconstruct The Bad Habits Holding You Back.

Get My Free Ebook


Post a comment