Complications have been observed primarily in patients wearing soft contact lenses. These include:
Infectious keratitis (corneal infiltrations and ulcers) caused by bacteria, fungi, and protozoans.
U Acanthamoeba keratitis is a serious complication affecting wearers of soft contact lenses and often requires penetrating keratoplasty.
Corneal vascularization may be interpreted as the result of insufficient supply of oxygen to the cornea.
Severe chronic conjunctivitis: This usually makes it impossible to continue wearing contact lenses.
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