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Chapter 8

Case 8-1. Soft Drusen

Clinical Summary

A 58-year-old woman with the clinical diagnosis of age-related macular degeneration had dense, soft dm sen in her right central macula (A). No subretinal fluid, hemorrhage, or exudate were noted on clinical examination. Fluorescein angiography (B) displayed punctatehyperfluo-rescence without leakage during all phases of the angiogram consistent with the staining of soft drusen.

Optical Coherence Tomography

Small modulations in the contour of the retinal pigment epithelium were noted in a vertical OCT image (C) taken through the fovea. The lack of shadowing below these contour changes, usually a feature of serous detachments of the pigment epithelium, was consistent with the accumulation of soft drusen beneath the neurosensorv j retina and within Bruch's membrane,

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