Chapter 6

Case 6-5. Non-Proliferative Diabetic Retinopathy

Clinical Summary

A 63-year-old man with a visual acuity of 20/200 in his right eye had non-proliferative diabetic retinopathy and macular edema. Scattered dot and blot hemorrhages, microaneurysms, hard exudate, and diffuse macular thickening were noted on dilated fundus examination (A). Angiography revealed focal areas of hvperfluorescence in the macula which demonstrated late leakage of fluorescein dye consistent with microaneurysms (B).

Optical Coherence Tomography

A sequence of radially oriented, linear OCT tomograms (C) was obtained through the macula at different angular orientations. These images showed a diffuse increase in retinal thickness (480 am in the fovea), minimally reflective spaces corresponding to fluid accumulation in the outer retinal layers, and focal, intraretinal m areas of high backscattering corresponding to hard exudate.

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