Summary

Intestinal transplantation is an option for individuals who are otherwise committed to a life of HPN because of intestinal failure. Intestinal transplantation is a fairly new procedure, which is still evolving, and at this time is still associated with significant risks. Rejection in intestinal transplantation is controllable with current immunosuppressive drugs, provided it is identified early. Infectious complications are the most significant cause of morbidity and mortality with intestinal transplantation. Post transplant lymphoproliferative disorders are also more common after intestinal transplantation, particularity when multivisceral transplants are performed. New strategies for detecting rejection and preventing infection are needed for intestinal transplantation to achieve the level of success that has been achieved with other solid organ transplants.

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