The use of trimethoprim/sulfamethoxazole (TMP/SMX) reduces the incidence of UTIs and blood stream infections after renal transplantation. Such an approach offers additional protection against opportunistic pathogens such as P carinii, Listeria monocytogenes, and Nocardia species. For sulfa-sensitive recipients, fluoroquinolones are alternative prophylaxis agents. Typically, prophylaxis is continued for six months after transplantation.

To prevent surgical wound infections, a cephalosporin antibiotic is administered peri-operatively and continued for less than 24 hours.

Heart Transplantation

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