Pneumonia is a very common complication of lung transplantation, with an overall prevalence of 60% in lung recipients. The heightened susceptibility to lung infection stems from several factors related to the allograft such as impaired cough reflex of the lung allograft, poor mucociliary clearance, ischemia to the explanted lung, abnormal lymphatic drainage, diffuse reperfusion injury, and airway inflammation caused by rejection and resulting in bacterial colonization. After single lung transplantation, the allograft may become infected from the remaining native lung. Gram-negative bacteria, including the Enterobacteriaceae and P. aeruginosa, account for the majority of post-transplant pneumonias. Other important pathogens are S. aureus, H. influenzae, and Streptococcus pneumoniae. B. cepacia colonization is associated with high morbidity and mortality after transplantation for cystic fibrosis.

Mediastinitis and sternal wound infections are other important post-operative infections in lung transplant recipients. The most serious complications after lung transplantation are leakage or dehiscence of the bronchial or tracheal anastomosis.

Dealing With Asthma Naturally

Dealing With Asthma Naturally

Do You Suffer From ASTHMA Chronic asthma is a paralyzing, suffocating and socially isolating condition that can cause anxiety that can trigger even more attacks. Before you know it you are caught in a vicious cycle Put an end to the dependence on inhalers, buying expensive prescription drugs and avoidance of allergenic situations and animals. Get control of your life again and Deal With Asthma Naturally

Get My Free Ebook

Post a comment