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day at 1 month and then to a maintenance dosage of 0.25 mg/kg/day at 1 year post transplant), and azathioprine (5 mg/kg/day tapered to 2.5 mg/kg/day by post transplant day 7) are started on the day of transplant. For maintenance immunosuppression, most centers use either CsA or FK506 (with or without rapamycin), MMF or AZA, and prednisone. Cyclosporine (2.5 mg/kg twice a day) or FK506 (.10 to .30 mg/kg twice a day) is added when serum creatinine is <3 mg/dl and levels are measured periodically.

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