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Previous Thoracic Surgery

Previous thoracic surgery or pleurodesis is not a specific contraindication to lung transplantation. Some patients with emphysema are candidates for lung volume reduction before transplantation. Adhesions and anatomic distortion from previous thoracic surgical procedures complicate the conduct of the explantation and transplantation procedures and must be taken into consideration in planning the operative procedure.

Malignancy

History of malignant disease within the previous 5 years is usually a contraindication to transplantation. A patient judged to be cured of a more recent malignancy might be considered. An exception to this is the rare patient with bronchoalveolar carcinoma without metastatic disease. These patients have been successfully transplanted in some programs.3

Smoking

Patients who continue to smoke are not candidates for transplantation.

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