History

The first successful series of pediatric heart transplants were reported out of Pittsburgh and Stanford. Fricker reported 14 transplants performed between 1981 and 1986 in children aged 2-16 years, with 8 long-term survivors.1 Starnes reported 17 children aged 5 months to 14 years transplanted between 1981 and 1988 with 13 long-term survivors.2 It was the introduction of Cyclosporine for immunosuppression that made success in pediatric heart transplantation possible. Neonatal cardiac transplantation was first performed by Leonard Bailey at Loma Linda University in 1985.3 Pediatric heart transplants currently account for approximately 10% of all cardiac transplants.4 Worldwide, there are approximately 200 centers performing pediatric heart transplants and since 1990 the number of pediatric heart transplants performed per year has been relatively constant, between 350 and 400.5

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