Conclusion

Transplantation has become the treatment of choice for patients with end-stage organ failure. Results have improved due to refinements in surgical technique, immunosuppression, preservation, and patient management. Unfortunately, organ donation has not kept pace with the ever-increasing demand for transplantation. Although the techniques described in this chapter on organ procurement and preservation are important, they cannot be applied without the generous gift of organ donation. This is also true for nearly every other advance made in clinical transplantation. Therefore, increasing the number of patients who receive the gift of life through increased organ donation must now be our highest priority.

Selected Readings

1. Institute of Medicine. Non-Heart-Beating Organ Transplantation: Medical and Ethical Issues in Procurement. Washington DC: National Academy Press, 1997.

2. D'Alessandro AM, Hoffmann RM, Knechtle SJ et al. Liver transplantation from controlled non-heart-beating donors. Surgery 2000; 128:579-588.

3. D'Alessandro AM, Odorico JS, Knechtle SJ et al. Simultaneous pancreas-kidney (SPK) transplantation from controlled non-heart-beating donors (NHBDs). Cell Transplant 2000; 9:889-893.

4. Kauffman HM, Bennett LE, McBride MA et al. The expanded donor. Transplant Rev 1997; 11:165-190.

5. The Multi-Organ Donor: Selection and Management. RSD Higgins, JA Sanchez, MI Lorber, JC Baldwin, Eds. Malden, MA, Blackwell Science, 1997.

6. Sollinger HW, Odorico JS, Knechtle SJ et al. Experience with 500 simultaneous pancreas-kidney transplants. Ann Surg 1998; 228:284-296.

8. Problems in General Surgery, Vol. 15: Organ Transplantation. RJ Stratta, Ed. Philadelphia, Lippincott Williams & Wilkins, 1998.

9. D'Alessandro AM, Hoffmann RM, Southard JH. Solution development in organ preservation: the University ofWisconsin perspective. Transplant Rev 1999; 13:1-12.

10. Zaroff JG, Rosengard BR, Armstrong WF et al. Consensus Conference Report-Maximizing use of organs recovered from the cadaver donor: cardiac recommendations. Circulation 2002; 106:836-841.

11. Weber M, Dindo D, Demartines N et al. Kidney transplantation from donors without a heartbeat. N Engl J Med. 2002; 347:248-255.

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