Clinical Presentation

This fungus has a strong predilection for the central nervous system, causing meningitis and, occasionally, brain abscesses. Patients present subacutely with low-grade temperature, headache, and altered mental status. Signs of frank men-ingismus are usually absent. Alternate presentations include pulmonary disease with pneumonitis, nodules, and lung abscess; soft tissue, skin or joint infection; and fever of unknown origin.

The diagnosis of cryptococcosis is made by the detection of antigen in serum and CSF. Examination of the CSF is required in any transplant recipient who presents with cryptococcal infection from any site. With meningitis, the CSF analysis demonstrates lymphocytic pleocytosis, elevated protein, and low glucose; the opening pressure is elevated. Fungal cultures of CSF and blood should be performed.

Naturally Cure Your Headaches

Naturally Cure Your Headaches

Are Headaches Taking Your Life Hostage and Preventing You From Living to Your Fullest Potential? Are you tired of being given the run around by doctors who tell you that your headaches or migraines are psychological or that they have no cause that can be treated? Are you sick of calling in sick because you woke up with a headache so bad that you can barely think or see straight?

Get My Free Ebook


Post a comment