Clinical Presentation

Patients present subacutely with fever, dyspnea, and nonproductive cough. The classic radiographic finding is bilateral diffuse interstitial and alveolar infiltrates. The laboratory evaluation reveals elevated lactate dehydrogenase (LDH) levels and hypoxemia. The definitive diagnosis is made by direct staining of induced sputum, bronchoalveolar lavage, or lung tissue specimens with fluorescent monoclonal antibodies, methenamine silver, calcofluor white, or Wright-Giemsa stain. Co-infection with CMV can occur and requires investigation.

0 0

Post a comment