As mentioned above the most morphologically distinctive and recognizable (but not necessarily the commonest variant encountered) primary lymphoma is MZBL of
Stage I El Primary thyroid lymphoma (PTL) with or without perithyroidal soft tissue extension. Stage [IE: PTLs with involvement of lymph nodes on the same side of the diaphragm. Stage iTIE; PTLs with involvement of lymph nodes on both sides of the diaphragm. Stage IV E; PTLs with dissemination to other extranodal sites.
MALT type. Others seen include: MZBL of MALT type with large cell (blastic) transformation (mixed MZBL and diffuse large B cell lymphoma [DLBCL]), DLBCL without MZBL and a miscellaneous, heterogenous group usually consisting of single case reports of a wide variety of lymphomas that can occur in lymph nodes and any other extranodal site. These include: Hodgkin's disease, follicular lymphoma, intravas-cular lymphomatosis, anaplastic large cell lymphoma and T-cell lymphomas (35-42). These will not be dealt with, as their occurrence in the thyroid is the same as any other extra-nodal site or lymph node for that matter.
The high-grade lesions: mixed MZBL/DLBCL and DLBCL without MZBL are the commonest histological types of primary thyroid lymphoma that are encountered (36, 42).
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