In the last 10 or so years lymphoma classification has undergone a major revision with the appearance of the Revised European-American Lymphoma (REAL) classification (25-27) and the subsequent World Health Organization (WHO) update, refinement and minor modification of the REAL classification (28-34). After Isaacson and Wright brought the concept of MALT and lymphomas arising therefrom to prominence, the terms MALT lymphoma or lymphoma arising in MALT or "MALT-oma" have been used. The advent of the REAL/WHO classifications led to a re-appraisal, and these peculiar and characteristic lymphomas were categorized as: extra-nodal marginal zone B-cell lymphomas (MZBL) of MALT-type. This is the prototype lymphoma occurring primarily in the thyroid. Variants and other common related lymphomas will be discussed.
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