Mixed Follicularc Cell Lesions

Although controversial, mixed follicular-parafollicular cell carcinomas do occur (253); these rare monomorphous tumours are composed of cells showing dual differentiation (254,255). Composite tumors are composed of two intermixed well differentiated components, one showing thyroglobulin immunoreactivity and either papillary or follicular architecture and cytology, the other with calcitonin and CEA immunopositivity (81,256). The diagnosis of a mixed or composite tumor can be convincing only in cases where metastatic disease is identified, since the identification of thyroglobulin and calcitonin in a primary intrathyroidal tumor may represent the identification of a typical medullary thyroid carcinoma with trapped nontumorous elements containing thyroglobulin, or phagocytosis of thyroglobulin by medullary carcinoma cells. Moreover, the two tumours may occur separately in the same gland and metastasise together to a regional node (257,258).

Was this article helpful?

0 0
10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook

Post a comment