Thyroid tumors are common neoplasms that exhibit a wide range of biologic behavior. Numerous factors have been shown to govern thyrocyte proliferation. In particular, hormones and growth factors likely play a role as promoters of tumor cell growth in genetically transformed cells. In some instances enhanced growth factors and their receptors may serve as survival signals for neoplastic cells. In other instances, however, abnormal forms of growth factor receptors (such as members of the EGF-R/HER2/neu) may also be important in the early stages of cell transformation and chromosomal instability consistent with the clonal composition of thyroid neoplasms. More detailed structure/function studies of growth factor/receptor functional interactions in morphologically characterized thyroid nodules are required. It is anticipated that these studies will identify signaling patterns that will provide the basis for the development of more specific and effective pharmacotherapeutic agents.

Was this article helpful?

0 0
10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook

Post a comment