Conclusions

We can see that while the past 5 years have increased our understanding of the transport of pre- and postsynaptic molecules, large gaps in our knowledge of this process still exist. Questions that remain to be addressed largely center around the molecular mechanisms which govern the transport of postsynaptic molecules and that are directly responsible for their recruitment to newly forming synapses. In light of the fact that the formation of synapses is of the utmost importance to brain function, where even subtle errors lead to devastating disorders of the mind, such as autism, mental retardation, and perhaps even schizophrenia, it is critical that we unravel the mysteries of protein trafficking in developing neurons.

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