Intravenous lines

These should be set up for fluid replacement and drug administration (preferably with 0 9% sodium chloride (normal or physiological saline) rather than 5% glucose solutions). Drugs should not be mixed and, if two antiepileptic drugs are needed (for example, phenytoin and diazepam), two intravenous lines should be sited. The lines should be in large veins, as many antiepileptic drugs cause phlebitis and thrombosis at the site of infusion. Arterial lines must never be used for drug administration to avoid the risk of arterial necrosis.

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