Cerebral protection

Considerable effort72 has gone towards the development of a neuroprotective agent, or agents, that could be given after brain trauma to reduce mortality and improve functional recovery. There have been many failed or inconclusive studies to date and the future of pharmacological neuroprotection after TBI remains in doubt. Clinicians managing patients with a head injury are therefore left with detection and prevention of secondary insults to the brain, including management of medical complications of brain injury, and non-pharmacological interventions that might beneficially modify the brain's response to trauma.

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