Tumours of bone and cartilage

The spectrum and clinicopathological features of nasopharyngeal tumours of bone and cartilage are similar to those of other sites in the upper aerodigestive tract, except for chordoma, which typically presents in the nasopharynx.

Chordoma

Definition

A low-grade malignant tumour that recapitulates the notochord.

ICD-O code 9370/3

Epidemiology

Chordomas account for approximately 4% of malignant bone tumours {2655}. About a third involve the base of the skull, and a small proportion may involve the nasopharynx and/or paranasal sinuses. There is a male predilection. The patients are predominantly adults, but children can also be affected.

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