Signs and symptoms

Adult laryngeal papillomas cause hoarseness {240,1253}. The disease is usually self-limiting.

Most children with laryngeal RRP present with dysphonia and stridor, less commonly with chronic cough, recurrent pneumonia, dyspnoea, and acute life-threatening events {178,240,587}. Delay, due to mistaken diagnoses, such as bronchitis, asthma, and other allergic manifestations, may lead to gradual respiratory distress and urgent tracheotomy, which is associated with more frequent extension into the tracheobronchial tree. The overall mortality rate of patients with

Fig. 3.44 Squamous papillomas of the larynx. A Higher magnification of a papillary branch. B Pronounced koilocytosis is evident in the upper part of the squamous epithelium. C Positive in-situ hybridization signal for HPV genotypes 6 and 11 in the upper part of the squamous epithelium.

RRP ranges from 4-14 % {126}, often due to asphyxia, infection, pulmonary complications, and malignant transformation {109,126,2437}.

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Coping with Asthma

Coping with Asthma

If you suffer with asthma, you will no doubt be familiar with the uncomfortable sensations as your bronchial tubes begin to narrow and your muscles around them start to tighten. A sticky mucus known as phlegm begins to produce and increase within your bronchial tubes and you begin to wheeze, cough and struggle to breathe.

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