Prognosis and predictive factors

LEC of the oral cavity and oropharynx are radiosensitive, and in a high percentage of cases local control can be achieved even in the presence of regional lymph node metastasis {1339}. Local, regional and distant failures occur in 3%, 5% and 19% of cases respectively {444}. Distant metastasis is associated with a poor prognosis.

Fig. 4.13 A Lymphoepithelial carcinoma of the tonsil. The tumour infiltrates beneath an intact surface epithelium. In this example, the tumour islands are obscured by the heavy lymphoplasmacytic infiltrate. B Sheets and islands of tumour cells intimately admixed with lymphocytes and plasma cells. C Lymphoepithelial carcinoma of the palate. Carcinoma cells exhibit indistinct cell borders, pale chromatin and distinct nucleoli. Many lymphocytes are found among the carcinoma cells.

Fig. 4.13 A Lymphoepithelial carcinoma of the tonsil. The tumour infiltrates beneath an intact surface epithelium. In this example, the tumour islands are obscured by the heavy lymphoplasmacytic infiltrate. B Sheets and islands of tumour cells intimately admixed with lymphocytes and plasma cells. C Lymphoepithelial carcinoma of the palate. Carcinoma cells exhibit indistinct cell borders, pale chromatin and distinct nucleoli. Many lymphocytes are found among the carcinoma cells.

N. Gale W. Westra

B.Z. Pilch J. Califano

D. Sidransky N. Johnson

A. El Naggar D.G. MacDonald

The pathologic assessment of precursor lesions is similar throughout the upper aerodigestive tract. It is described in detail in the Chapter 3 on tumours of the hypopharynx, larynx and trachea (page 140).

Was this article helpful?

0 0
10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook


Post a comment