Prognosis and predictive factors

These high-grade tumours are characterised by multiple local recurrences and regional or distant metastases {922,940}. In one series, 7 of 11 patients studied ultimately developed metastatic disease {1227}. It appears that the most important prognostic indicator is the presence or absence of distant metastases {1833}.

Fig. 5.23 Oncocytic carcinoma. A Invasion into the parotid gland. B Atypical tumour cells have prominent nucleoli and eosinophilic, granular cytoplasm. C Perineural invasion.

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