Prognosis and predictive factors

Prognosis correlates most strongly with clinical stage, emphasizing the importance of early diagnosis. The microscopic grade and tumour type have been shown to be independent predictors of behaviour and often play an important role in optimizing treatment {1264,1918, 2440,2447,2449,2519}. Locoregional failure of some types of salivary carcinomas results in a greater likelihood of distant metastasis indicating a need for aggressive initial surgery {2441}. As might be expected, there is often a positive correlation between grade and clinical stage.

G. Ellis

R.H.W. Simpson

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