Prognosis and predictive factors

Most cases of FDC sarcomas/tumours have been treated by surgery, with or without adjuvant chemotherapy and radiotherapy, with variable success. FDC sarcomas/tumours are low to intermediate grade malignant tumours, with an overall local recurrence rate of at least 40% and a metastatic rate of at least 28% {368,2010,2043}. Since some patients can develop late metastasis (such as after more than 20 years) {438}, long-term follow up is essential. Poor prognostic factors include significant cytologic atypia, extensive coagulative necrosis, high proliferative index and large tumour size {368,2010}.

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