Oa I


Fig. 4.46 Primary large B cell lymphoma of the oral cavity and oropharynx: cytological spectrum. A Large cells with predominantly round nuclei and membrane bound nucleoli, consistent with centroblastic morphology. B Predominantly medium-sized cells with abundant pale cytoplasm. C Large cells with round or multi lobated nuclei.

conditions, such as periodontitis. Tonsillar lymphoma usually manifests as asymmetric tonsil enlargement, although the disease can be bilateral in up to 9% of cases {2250}. The regional lymph nodes can be enlarged as a result of lymphoma involvement or reactive changes secondary to ulceration.

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