Macroscopy

The macroscopic appearance of PLMMM vary and include nodular, mul-

Fig. 3.68 Primary laryngeal mucosal malignant melanoma. A Features that can be seen in melanomas include clear appearing cytoplasm. B Spindle cell PLMMM comprised of a hypercellular spindle-shaped proliferation with storiform growth pattern; scattered mitotic figures are present (arrows). C More often, tumours are devoid of readily apparent melanin (amelanotic melanomas) or the melanin deposition is limited to isolated cells.

Fig. 3.68 Primary laryngeal mucosal malignant melanoma. A Features that can be seen in melanomas include clear appearing cytoplasm. B Spindle cell PLMMM comprised of a hypercellular spindle-shaped proliferation with storiform growth pattern; scattered mitotic figures are present (arrows). C More often, tumours are devoid of readily apparent melanin (amelanotic melanomas) or the melanin deposition is limited to isolated cells.

berry-like, sessile, polypoid, exophytic or pedunculated lesions with equally variable colour, including black, brown, red-pink, tan-grey and white {2754}. The size of the tumours range from 3-4 mm up to 8.0 cm in greatest dimension {2754}.

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