Macroscopy

The majority of tumours are firm, polypoid or sessile, and less than two centimetres. They are covered by an intact (rarely ulcerated) mucosa, and on cross section are grey-white or yellow.

Fig. 3.59 Granular cell tumour. A Periodic acid-Schiff (PAS) stain with diastase accentuates the cytoplasmic granularity. B The granularity of the cytoplasm is due to lyosomes. C Strong immunoreactivity for S-100 protein.

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