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Fig. 5.52 Pleomorphic adenoma. Partial G-banded and complete SKY karyotypes of a pleomorphic adenoma showing the most common abnormality, a t(3;8)(p21;q12) translocation. Breakpoints on marker chromosomes are indicated by arrowheads.

Fig. 5.52 Pleomorphic adenoma. Partial G-banded and complete SKY karyotypes of a pleomorphic adenoma showing the most common abnormality, a t(3;8)(p21;q12) translocation. Breakpoints on marker chromosomes are indicated by arrowheads.

Fig. 5.53 Pleomorphic adenoma. Schematic illustration of the five PLAG1 and HMGA2 gene fusions specific and diagnostic for pleomorphic adenomas.

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