Keratoacanthomas preferentially occur on sun exposed hairy skin {881}. Thus, they are frequent on the skin of the face, including the lips (8% of cases), and extremely rare at hairless sites. Whether or not a "true keratoacanthoma" of the oral mucosa exists or not remains controversial {1929}. However, a small number of cases of the solitary form have been reported in intraoral sites {414,973}, and mucocutaneous linings may also be affected in the generalized forms (e.g. the Ferguson-Smith, Grzybowski and Witten and Zak types) {881}.

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