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Fig. 4.21 Papilloma. A Typical papillary structure of squamous papilloma. This example is only lightly kera-tinised and negative for papilloma virus on immunocytochemistry. B Papilloma from the vermillion border showing extensive keratinisation. Note the inwardly facing rete ridges at the periphery. C Moderately ker-atinised papilloma of verruca vulgaris type showing koilocytic change in the upper prickle cell layers. D Strong and extensive staining for papilloma virus in a flat papilloma from an HIV infected individual. There is widespread infection in the upper prickle cell layer but the architecture of the epithelium is little changed. Note the sharp lesion margin on the left.

Fig. 4.21 Papilloma. A Typical papillary structure of squamous papilloma. This example is only lightly kera-tinised and negative for papilloma virus on immunocytochemistry. B Papilloma from the vermillion border showing extensive keratinisation. Note the inwardly facing rete ridges at the periphery. C Moderately ker-atinised papilloma of verruca vulgaris type showing koilocytic change in the upper prickle cell layers. D Strong and extensive staining for papilloma virus in a flat papilloma from an HIV infected individual. There is widespread infection in the upper prickle cell layer but the architecture of the epithelium is little changed. Note the sharp lesion margin on the left.

cous dysplastic lesions and papillary squamous {2488} or verrucous carcinoma. Florid oral papillomatosis is a clinical term for diffuse papillomatous change of the mucosa for which no specific cause can be identified and is not a defined clinico-pathological entity.

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