ICDO codes

Acinic cell carcinoma 8550/3 Mucoepidermoid carcinoma


Adenoid cystic carcinoma


Polymorphous low-grade adenocarcinoma 8525/3

Epithelial-myoepithelial carcinoma 8562/3

Clear cell carcinoma, NOS 8310/3

Basal cell adenocarcinoma 8147/3

Cystadenocarcinoma 8450/3 Mucinous adenocarcinoma


Oncocytic carcinoma 8290/3 Salivary duct carcinoma 8500/3 Myoepithelial carcinoma 8982/3 Carcinoma ex pleomorphic adenoma 8941/3

Acinic cell carcinoma

These are uncommon in minor glands {9, 280,340,410,734,864,2886} and form 26.5% of all intraoral salivary gland tumours {669,704,2711}. In one series, the age range was from 11-77 years, with a mean of 45 years, and a male to female ratio of 1.5:1 {2711}. The most common sites are the buccal mucosa, upper lip and palate where the tumours usually form non-descript swellings. The microscopical features are similar to those in major glands. However, in one series there appeared to be more areas consisting of solid sheets of epithelium with secretory material and fewer areas show-

the minor glands {2711}.

Mucoepidermoid carcinoma This most common malignant salivary gland tumour involves minor glands, and accounts for 9.5-23% of all minor gland tumours {669,704,2711}. About half of the cases arise in the palate and other common sites include the buccal mucosa, lips, floor of oral cavity and retromolar pad. They appear to be much more frequent in the lower lip than the upper lip {1871}.

The tumour is often asymptomatic and detected during a routine dental examination. Many appear as bluish, domed swellings that resemble mucoceles or haemangiomas. Less commonly, the surface appears granular or papillary. Tumours of the base of tongue or oropharynx may cause dysphagia and sublingual tumours can lead to anky-loglossia and dysphonia. High-grade tumours are uncommon but can result in ulceration, loosening of teeth, paraesthe-sia or anaesthesia. Mucoepidermoid carcinoma is the most common salivary gland tumour to develop in a central location within the bone of the mandible or, less frequently, the maxilla {280}. The microscopical features of minor gland mucoepidermoid carcinomas are the same as those seen in the major glands.

Adenoid cystic carcinoma

This lesion is relatively common in the minor glands. In the AFIP series 42.5% of all adenoid cystic carcinomas were in minor glands and 20.5% of the total was

Table 4.04 Percentage of malignant minor salivary gland tumours in different sites in published series.

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