ICDO code80513

This rare variant of oral cancer has similarities to the lesion more commonly described in the foot in which tumour infi-trates deeply into bone. The oral tumours show proliferation of stratified squamous epithelium in broad processes with keratin cores and keratin filled crypts which seem to burrow into bone, but lack obvious cytological features of malignancy {40}. Diagnosis on biopsy specimens can be very difficult and correlation with the clinical and radiographic features is required.

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