I

Fig. 5.20 Low-grade cribriform cystadenocarcinoma (LGCCC) A The intraductal proliferations of LGCCC resemble benign breast ductal hyperplasia. The fenestrations formed are "floppy", not rigid. B Calponin, a myoepithelial marker, highlights the largely intraductal nature of this neoplasm. LGCCC strongly expresses S100, in distinction to the papillocystic variant of acinic cell carcinoma. C Golden-brown pigment can be see within the relatively bland tumour cells of LGCCC.

Low-grade cribriform cystadenocarcinoma 233

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