Histopathology

PLMMM are identical to melanomas at other sites.

In the presence of an intact laryngeal mucosa, continuity of the tumour with the surface epithelium (i.e., junctional or pagetoid changes) can be identified; however, even in the presence of intact surface epithelium, junctional changes may not be seen. Given the fact that normal melanocytes may localize to the sub-mucosal compartment within minor mucoserous glands or within the stroma {2754,2755}, junctional change is not required to render a diagnosis of PLMMM.

Fig. 3.70 Primary laryngeal mucosal malignant melanoma. Prominent and obvious intracytoplasmic melanin deposition is seen in this PLMMM; this extent of melanin deposition is unusual for MMM.

Was this article helpful?

0 0
10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook


Post a comment