Etiology

Whether RMs are hamartomas or true neoplasms is controversial. Cytogenetics examination of an ARM has demonstrated clonal chromosomal abnormalities which supports a neoplastic origin {886}. Extracardiac RMs should be distinguished from those in the heart. Cardiac RMs are hamartomas and often associated with tuberous sclerosis. Extracardiac RMs, with the rare exception of a FRM

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