Etiology

There is no known etiology in most patients. A minority of patients have an underlying immunodeficiency state (e.g. HIV infection, post-transplantation), which predisposes to the development of NHL. There is a strong association with Epstein-Barr virus (EBV) for lymphomas occurring in the setting of immunodeficiency as well as in extranodal NK/T cell

Table 4.06 Frequency of the various types of primary lymphoma of the tonsil {1704}

Diffuse large B-cell lymphoma (DLBCL) " ICD-O code 9680/3

64%

Mantle cell lymphoma ICD-O code 9673/3

10%

Follicular lymphoma ICD-O code 9690/3

8%

Extranodal marginal zone B-cell lymphoma of MALT type* ICD-O code 9699/3

6.5%

T-cell lymphoma (including anaplastic large cell lymphoma ICD-O code 9714/3)

6.5%

Burkitt lymphoma ICD-O code 9687/3

5%

* Reported as monocytoid B-cell immunocytoma in the original series.

lymphoma and

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