Contents

1 Nasal cavity and paranasal sinuses 9

WHO and TNM classification 10

Introduction 12 Malignant epithelial tumours

Squamous cell carcinoma 15

Lymphoepithelial carcinoma 18

Sinonasal undifferentiated carcinoma 19

Adenocarcinoma 20

Salivary gland-type carcinomas 24

Neuroendocrine tumours 26 Benign epithelial tumours

Schneiderian papillomas 28 Respiratory epithelial adenomatoid hamartoma 33

Salivary gland-type adenomas 34 Soft tissue tumours

Malignant soft tissue tumours 35

Borderline and LMP tumours 43

Benign soft tissue tumours 46 Tumours of bone and cartilage

Malignant tumours 51

Benign tumours 53

Haematolymphoid tumours 58

Neuroectodermal tumours 65

Germ cell tumours 76

Secondary tumours 80

2 Nasopharynx 81

WHO and TNM classification 82

Introduction 83 Malignant epithelial tumours

Nasopharyngeal carcinoma 85

Papillary adenocarcinoma 98

Salivary gland-type carcinomas 98

Benign epithelial tumours 99

Nasopharyngeal angiofibroma 102

Haematolymphoid tumours 104

Tumours of bone and cartilage 106

Secondary tumours 106

3 Hypopharynx, larynx and trachea 107

WHO and TNM classification 108

Introduction 111 Malignant epithelial tumours

Squamous cell carcinoma 118

Verrucous carcinoma 122

Basaloid squamous cell carcinoma 124

Papillary squamous cell carcinoma 126

Spindle cell carcinoma 127

Acantholytic squamous cell carcinoma 129

Adenosquamous carcinoma 130

Lymphoepithelial carcinoma 132

Giant cell carcinoma 133

Malignant salivary gland-type tumours 134

Neuroendocrine tumours 135

Epithelial precursor lesions 140 Benign epithelial tumours

Papilloma / papillomatosis 144

Benign salivary gland-type tumours 146

Malignant soft tissue tumours 147

Inflammatory myofibroblastic tumour 150

Benign soft tissue tumours 152

Haematolymphoid tumours 155

Tumours of bone and cartilage 156

Mucosal malignant melanoma 160

Secondary tumours 162

4 Oral cavity and oropharynx 163

WHO and TNM classification 164

Introduction 166 Malignant epithelial tumours

Squamous cell carcinoma 168

Lymphoepithelial carcinoma 176

Epithelial precursor lesions 177

Proliferative verrucous leukoplakia 180

Precancerous conditions 180 Benign epithelial tumours

Papillomas 182

Granular cell tumour 185

Keratoacanthoma 187

Papillary hyperplasia 189

Median rhomboid glossitis 189

Salivary gland tumours 190

Kaposi sarcoma 193

Lymphangioma 195

Ectomesenchymal chondromyxoid tumour 196

Focal oral mucinosis 197

Congenital granular cell epulis 198

Haematolymphoid tumours 199

Malignant melanoma 206

Secondary tumours 208

5 Salivary glands 209

WHO and TNM classification 210

Introduction 212 Malignant epithelial tumours

Acinic cell carcinoma 216

Mucoepidermoid carcinoma 219

Adenoid cyctic carcinoma 221

Polymorphous low-grade adenocarcinoma 223

Epithelial-myoepithelial carcinoma 225

Clear cell carcinoma, N.O.S. 227

Basal cell adenocarcinoma 229

Malignant sebaceous tumours 231

Cystadenocarcinoma 232

Low-grade cribriform cystadenocarcinoma 233

Mucinous adenocarcinoma 234

Oncocytic carcinoma 235

Salivary duct carcinoma 236

Adenocarcinoma, N.O.S.

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