Clinical features

Patients with NHL of the lip, buccal mucosa, gingiva, floor of mouth, tongue or palate usually present with ulcer, swelling, discoloration, pain, paraesthe-sia, anaesthesia, or loose teeth. Those with NHL of the Waldeyer ring (tonsils) or oropharynx usually present with a sensation of fullness of the throat, sore throat, dysphagia, or snoring. The high-grade tumours often show rapid growth. Systemic symptoms such as fever and night sweat are uncommon {201}. Clinical examination reveals solitary or multiple lesions, in the form of an exo-phytic mass, ulcer or localized swelling. Some cases may mimic inflammatory

Lymphoma Lesions The Tongue
Fig. 4.45 A Primary large B cell lymphoma of the lip. The mucosa shows a diffuse infiltrate of lymphoma cells beneath an intact stratified squamous epithelium. B Primary large B cell lymphoma of the tongue. In this example, the mucosa is partly ulcerated.

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