capillary network that irrigates the brain. This vascular penetration and subsequent differentiation continue until the end of the first trimester, during which time CAVMs are thought to develop. Once formed, extrinsic factors such as arterial shunting, growth factors or intracranial hemorrhage may alter a CAVM's morphology.

There are a small number of rare congenital syndromes such as Sturge-Weber, Rendu-Osler-Weber, ataxia telangiectasia and Wyburn-Mason that are associated with CAVMs. Sturge-Weber syndrome, or encephalotrigemi-nal angiomatosis, has two key pathological components: a cutaneous, facial angioma in the distribution of the trigeminal nerve, and an ipsilateral, parietal-occipital vascular malformation. In Sturge-Weber syndrome, the intracranial vascular malformation is pial based and rarely causes intracranial hemorrhage. However, it may cause intractable epilepsy, mental retardation and progressive encephalo-malacia. Rendu-Osler-Weber syndrome, or hereditary hemorrhagic telangiectasia, is an autosomal-dominant syndrome of multiple visceral, mucosal and cerebral vascular malformations. Patients with Rendu-Osler-Weber syndrome usually present with recurrent epistaxis or cerebral infarcts from pulmonary AVM emboli. Ataxia telangiectasia and Wyburn-Mason syndrome may have cerebellar or dien-cephalic vascular malformations, respectively.

How To Deal With Rosacea and Eczema

How To Deal With Rosacea and Eczema

Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.

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