Cerebral metastases generally carry a very poor prognosis when not treated. The median survival for patients with symptomatic brain metastases that are not treated is 4-6 weeks. The optimal treatment of brain metastases must consider several factors, including the patient's neurologic and general medical condition, the number, location and size of the lesions, and the histology, the extent, the prior treatment and the response to treatment of the systemic disease. Two current trends in the approach to cerebral metastasis are evident: a shift from mere palliation of symptoms to tumor eradication, in an effort to improve survival, and an increased emphasis on the patient's quality of life. Three main modalities of treatment are used for brain metastases: radiation, surgery and chemotherapy.
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The term vaginitis is one that is applied to any inflammation or infection of the vagina, and there are many different conditions that are categorized together under this ‘broad’ heading, including bacterial vaginosis, trichomoniasis and non-infectious vaginitis.