High-grade gliomas include malignant variants of tumors derived from astrocytic and oligodendropheral cell lines. These tumors demonstrate invasive behavior, are rapidly growing and are usually characterized by contrast enhancement and edema on MR or CT neuroimaging. Management includes either biopsy or surgical resection followed by radiotherapy in the majority of cases. Additional adjuvant chemotherapy is also a treatment consideration. Despite advances in management, the prognosis remains poor, with few patients surviving beyond 2-3 years.
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The term vaginitis is one that is applied to any inflammation or infection of the vagina, and there are many different conditions that are categorized together under this ‘broad’ heading, including bacterial vaginosis, trichomoniasis and non-infectious vaginitis.